Single- and Multiple-Dose Trials to Determine the Pharmacokinetics, Safety, Tolerability, and Sex Effect of Oral Ginsenoside Compound K in Healthy Chinese Volunteers

Background and objectives: Ginsenoside compound K (CK) is a candidate drug for rheumatoid arthritis therapy. The objective of this study was to investigate the pharmacokinetic properties, safety and tolerability of CK. Methods: In randomized, double-blind trials, 76 healthy Chinese subjects received...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Lulu, Zhou, Luping, Huang, Jie, Wang, Yaqin, Yang, Guoping, Tan, Zhirong, Wang, Yicheng, Zhou, Gan, Liao, Jianwei, Ouyang, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769417/
https://ncbi.nlm.nih.gov/pubmed/29375375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00965
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