In Vitro and In Vivo Activities of Macrolide Derivatives against Mycobacterium tuberculosis

Existing macrolides have never shown definitive clinical efficacy in tuberculosis. Recent reports suggest that ribosome methylation is involved in macrolide resistance in Mycobacterium tuberculosis, a mechanism that newer macrolides have been designed to overcome in gram-positive bacteria. Therefore...

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Bibliografische gegevens
Hoofdauteurs: Falzari, Kanakeshwari, Zhu, Zhaohai, Pan, Dahua, Liu, Huiwen, Hongmanee, Poonpilas, Franzblau, Scott G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Clinical Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068601/
https://ncbi.nlm.nih.gov/pubmed/15793125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1447-1454.2005
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