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In Vitro and In Vivo Activities of Macrolide Derivatives against Mycobacterium tuberculosis
Existing macrolides have never shown definitive clinical efficacy in tuberculosis. Recent reports suggest that ribosome methylation is involved in macrolide resistance in Mycobacterium tuberculosis, a mechanism that newer macrolides have been designed to overcome in gram-positive bacteria. Therefore...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1068601/ https://ncbi.nlm.nih.gov/pubmed/15793125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1447-1454.2005 |
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