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Molecular Cloning and Physical Mapping of the Daptomycin Gene Cluster from Streptomyces roseosporus

The daptomycin biosynthetic gene cluster of Streptomyces roseosporus was analyzed by Tn5099 mutagenesis, molecular cloning, partial DNA sequencing, and insertional mutagenesis with cloned segments of DNA. The daptomycin biosynthetic gene cluster spans at least 50 kb and is located about 400 to 500 k...

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Detalhes bibliográficos
Main Authors: Mchenney, Margaret A., Hosted, Thomas J., Dehoff, Bradley S., Rosteck, Paul R., Baltz, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC106860/
https://ncbi.nlm.nih.gov/pubmed/9422604
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