Improvement of Daptomycin Production in Streptomyces roseosporus through the Acquisition of Pleuromutilin Resistance

Daptomycin, a cyclic lipopeptide antibiotic produced by Streptomyces roseosporus, displays potent activity against a variety of gram-positive pathogens. There is a demand for generating high-producing strains for industrial production of this valuable antibiotic. Ribosome engineering is a powerful s...

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Autori principali: Li, Linli, Ma, Tingmei, Liu, Qing, Huang, Yuqi, Hu, Changhua, Liao, Guojian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782809/
https://ncbi.nlm.nih.gov/pubmed/24106707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/479742
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