Isolation, Characterization, and Heterologous Expression of the Novel Lantibiotic Epicidin 280 and Analysis of Its Biosynthetic Gene Cluster

Epicidin 280 is a novel type A lantibiotic produced by Staphylococcus epidermidis BN 280. During C(18) reverse-phase high-performance liquid chromatography two epicidin 280 peaks were obtained; the two compounds had molecular masses of 3,133 ± 1.5 and 3,136 ± 1.5 Da, comparable antibiotic activities...

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Bibliografische Detailangaben

Veröffentlicht in:	Appl Environ Microbiol
Hauptverfasser:	Heidrich, Christoph, Pag, Ulrike, Josten, Michaele, Metzger, Jörg, Jack, Ralph W., Bierbaum, Gabriele, Jung, Günther, Sahl, Hans-Georg
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Food Microbiology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9726851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.64.9.3140-3146.1998
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