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Isolation, Characterization, and Heterologous Expression of the Novel Lantibiotic Epicidin 280 and Analysis of Its Biosynthetic Gene Cluster

Epicidin 280 is a novel type A lantibiotic produced by Staphylococcus epidermidis BN 280. During C(18) reverse-phase high-performance liquid chromatography two epicidin 280 peaks were obtained; the two compounds had molecular masses of 3,133 ± 1.5 and 3,136 ± 1.5 Da, comparable antibiotic activities...

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Autors principals: Heidrich, Christoph, Pag, Ulrike, Josten, Michaele, Metzger, Jörg, Jack, Ralph W., Bierbaum, Gabriele, Jung, Günther, Sahl, Hans-Georg
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC106701/
https://ncbi.nlm.nih.gov/pubmed/9726851
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