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Gene conversion and deletion frequencies during double-strand break repair in human cells are controlled by the distance between direct repeats

Homologous recombination (HR) repairs DNA double-strand breaks and maintains genome stability. HR between linked, direct repeats can occur by gene conversion without an associated crossover that maintains the gross repeat structure. Alternatively, direct repeat HR can occur by gene conversion with a...

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Detalhes bibliográficos
Main Authors: Schildkraut, Ezra, Miller, Cheryl A., Nickoloff, Jac A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065255/
https://ncbi.nlm.nih.gov/pubmed/15767282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki295
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