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Gene conversion and deletion frequencies during double-strand break repair in human cells are controlled by the distance between direct repeats

Homologous recombination (HR) repairs DNA double-strand breaks and maintains genome stability. HR between linked, direct repeats can occur by gene conversion without an associated crossover that maintains the gross repeat structure. Alternatively, direct repeat HR can occur by gene conversion with a...

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Autori principali: Schildkraut, Ezra, Miller, Cheryl A., Nickoloff, Jac A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1065255/
https://ncbi.nlm.nih.gov/pubmed/15767282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki295
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