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Relationship between Surface Accessibility for PpmA, PsaA, and PspA and Antibody-Mediated Immunity to Systemic Infection by Streptococcus pneumoniae

Antibodies to capsular polysaccharide (PS) are protective against systemic infection by Streptococcus pneumoniae, but the large number of pneumococcal serogroups and the age-related immunogenicity of pure PS limit the utility of PS-based vaccines. In contrast, cell wall-associated proteins from diff...

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Autori principali: Gor, Dennis O., Ding, Xuedong, Briles, David E., Jacobs, Michael R., Greenspan, Neil S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064945/
https://ncbi.nlm.nih.gov/pubmed/15731027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1304-1312.2005
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