Relationship between Surface Accessibility for PpmA, PsaA, and PspA and Antibody-Mediated Immunity to Systemic Infection by Streptococcus pneumoniae

Antibodies to capsular polysaccharide (PS) are protective against systemic infection by Streptococcus pneumoniae, but the large number of pneumococcal serogroups and the age-related immunogenicity of pure PS limit the utility of PS-based vaccines. In contrast, cell wall-associated proteins from diff...

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Detalhes bibliográficos
Main Authors: Gor, Dennis O., Ding, Xuedong, Briles, David E., Jacobs, Michael R., Greenspan, Neil S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064945/
https://ncbi.nlm.nih.gov/pubmed/15731027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1304-1312.2005
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