High expression of focal adhesion kinase (p125(FAK)) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome

INTRODUCTION: Focal adhesion kinase (FAK) regulates multiple cellular processes including growth, differentiation, adhesion, motility and apoptosis. In breast carcinoma, FAK overexpression has been linked to cancer progression but the prognostic relevance remains unknown. In particular, with regard...

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Detaylı Bibliyografya
Asıl Yazarlar: Schmitz, Klaus Jürgen, Grabellus, Florian, Callies, Rainer, Otterbach, Friedrich, Wohlschlaeger, Jeremias, Levkau, Bodo, Kimmig, Rainer, Schmid, Kurt Werner, Baba, Hideo Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2005
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064131/
https://ncbi.nlm.nih.gov/pubmed/15743500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr977
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