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Alphavirus replicon particles containing the gene for HER2/neu inhibit breast cancer growth and tumorigenesis
INTRODUCTION: Overexpression of the HER2/neu gene in breast cancer is associated with an increased incidence of metastatic disease and with a poor prognosis. Although passive immunotherapy with the humanized monoclonal antibody trastuzumab (Herceptin) has shown some effect, a vaccine capable of indu...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1064108/ https://ncbi.nlm.nih.gov/pubmed/15642163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr962 |
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