Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model

INTRODUCTION: The purpose of the present study was to determine whether cytotoxic chemotherapeutic agents administered prior to immunotherapy with gene vaccines could augment the efficacy of the vaccines. METHODS: Mice were injected in the mammary fat pad with an aggressive breast tumor cell line th...

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Autori principali: Eralp, Yesim, Wang, Xiaoyan, Wang, Jian-Ping, Maughan, Maureen F, Polo, John M, Lachman, Lawrence B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC468620/
https://ncbi.nlm.nih.gov/pubmed/15217493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr787
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