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Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model

INTRODUCTION: The purpose of the present study was to determine whether cytotoxic chemotherapeutic agents administered prior to immunotherapy with gene vaccines could augment the efficacy of the vaccines. METHODS: Mice were injected in the mammary fat pad with an aggressive breast tumor cell line th...

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Main Authors: Eralp, Yesim, Wang, Xiaoyan, Wang, Jian-Ping, Maughan, Maureen F, Polo, John M, Lachman, Lawrence B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC468620/
https://ncbi.nlm.nih.gov/pubmed/15217493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr787
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