Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

INTRODUCTION: Tamoxifen is effective for endocrine treatment of oestrogen receptor-positive breast cancers but ultimately fails due to the development of resistance. A functional screen in human breast cancer cells identified two BCAR genes causing oestrogen-independent proliferation. The BCAR1 and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dorssers, Lambert CJ, van Agthoven, Ton, Brinkman, Arend, Veldscholte, Jos, Smid, Marcel, Dechering, Koen J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2005
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064102/
https://ncbi.nlm.nih.gov/pubmed/15642172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr954
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg