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A Mutation in the Decoding Center of Thermus thermophilus 16S rRNA Suggests a Novel Mechanism of Streptomycin Resistance

A spontaneous kanamycin resistance and capreomycin resistance mutation, A1408G, in the decoding center of 16S rRNA, was identified in the extreme thermophile Thermus thermophilus. Unexpectedly, this mutation also confers resistance to streptomycin. We propose a novel mechanism of streptomycin resist...

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Bibliografiske detaljer
Main Authors: Gregory, Steven T., Carr, Jennifer F., Dahlberg, Albert E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064055/
https://ncbi.nlm.nih.gov/pubmed/15743969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.6.2200-2202.2005
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