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Epigenetic Mechanism of rRNA Gene Silencing: Temporal Order of NoRC-Mediated Histone Modification, Chromatin Remodeling, and DNA Methylation

Epigenetic control mechanisms silence about half of the rRNA genes in eukaryotes. Previous studies have demonstrated that recruitment of NoRC, a SNF2h-containing remodeling complex, silences rRNA gene transcription. NoRC mediates histone H4 deacetylation, histone H3-Lys9 dimethylation, and de novo D...

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Detalhes bibliográficos
Main Authors: Santoro, Raffaella, Grummt, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061655/
https://ncbi.nlm.nih.gov/pubmed/15767661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.7.2539-2546.2005
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