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Human mRNA Cap Methyltransferase: Alternative Nuclear Localization Signal Motifs Ensure Nuclear Localization Required for Viability
A characteristic feature of gene expression in eukaryotes is the addition of a 5′-terminal 7-methylguanine cap (m7GpppN) to nascent pre-mRNAs in the nucleus catalyzed by capping enzyme and cap methyltransferase. Small interfering RNA (siRNA) knockdown of cap methyltransferase in HeLa cells resulted...
Gorde:
Egile Nagusiak: | , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Microbiology
2005
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1061643/ https://ncbi.nlm.nih.gov/pubmed/15767670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.7.2644-2649.2005 |
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