Human Papillomavirus Type 16 E1(∧)E4-Induced G(2) Arrest Is Associated with Cytoplasmic Retention of Active Cdk1/Cyclin B1 Complexes

Human papillomavirus type 16 (HPV16) can cause cervical cancer. Expression of the viral E1(∧)E4 protein is lost during malignant progression, but in premalignant lesions, E1(∧)E4 is abundant in cells supporting viral DNA amplification. Expression of 16E1(∧)E4 in cell culture causes G(2) cell cycle a...

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Detalhes bibliográficos
Main Authors: Davy, Clare E., Jackson, Deborah J., Raj, Kenneth, Peh, Woei Ling, Southern, Shirley A., Das, Papia, Sorathia, Rina, Laskey, Peter, Middleton, Kate, Nakahara, Tomomi, Wang, Qian, Masterson, Phillip J., Lambert, Paul F., Cuthill, Scott, Millar, Jonathan B. A., Doorbar, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061520/
https://ncbi.nlm.nih.gov/pubmed/15767402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.3998-4011.2005
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