Central Role of Hemoglobin Degradation in Mechanisms of Action of 4-Aminoquinolines, Quinoline Methanols, and Phenanthrene Methanols

We have used a specific inhibitor of the malarial aspartic proteinase plasmepsin I and a nonspecific cysteine proteinase inhibitor to investigate the importance of hemoglobin degradation in the mechanism of action of chloroquine, amodiaquine, quinine, mefloquine (MQ), halofantrine, and primaquine. B...

Descrición completa

Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Mungthin, Mathirut, Bray, Patrick G., Ridley, Robert G., Ward, Stephen A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Assuntos:	Mechanisms of Action: Physiological Effects
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105975/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2973
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!