8-Aminoquinolines Active against Blood Stage Plasmodium falciparum In Vitro Inhibit Hematin Polymerization

From the Walter Reed Army Institute of Research (WRAIR) inventory, thirteen 8-aminoquinoline analogs of primaquine were selected for screening against a panel of seven Plasmodium falciparum clones and isolates. Six of the 13 8-aminoquinolines had average 50% inhibitory concentrations between 50 and...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Vennerstrom, Jonathan L., Nuzum, Edwin O., Miller, Robert E., Dorn, Arnulf, Gerena, Lucia, Dande, Prasad A., Ellis, William Y., Ridley, Robert G., Milhous, Wilbur K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.598
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