Antifungal Efficacy, Safety, and Single-Dose Pharmacokinetics of LY303366, a Novel Echinocandin B, in Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits

LY303366 is a novel semisynthetic derivative of echinocandin B and a potent inhibitor of fungal (1,3)-β-d-glucan synthase. The antifungal efficacy and safety of LY303366 were investigated in treatment and prophylaxis of primary pulmonary aspergillosis due to Aspergillus fumigatus in persistently neu...

Szczegółowa specyfikacja

Opis bibliograficzny

Wydane w:	Antimicrob Agents Chemother
Główni autorzy:	Petraitis, Vidmantas, Petraitiene, Ruta, Groll, Andreas H., Bell, Aaron, Callender, Diana P., Sein, Tin, Schaufele, Robert L., McMillian, Carl L., Bacher, John, Walsh, Thomas J.
Format:	Artigo
Język:	Inglês
Wydane:	American Society for Microbiology (ASM) 1998
Hasła przedmiotowe:	Experimental Therapeutics
Dostęp online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105963/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2898
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