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Role of osteopontin in amplification and perpetuation of rheumatoid synovitis

Osteopontin (OPN) is an extracellular matrix protein of pleiotropic properties and has been recently recognized as a potential inflammatory cytokine. In this study, we demonstrate, for the first time to our knowledge, that overexpression of OPN in synovial T cells is associated with local inflammato...

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Autores principales: Xu, Guangwu, Nie, Hong, Li, Ningli, Zheng, Wenxin, Zhang, Dongqing, Feng, Guozhang, Ni, Liqing, Xu, Rong, Hong, Jian, Zhang, Jingwu Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1059449/
https://ncbi.nlm.nih.gov/pubmed/15761492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523273
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