Characterization of a Glycosyl Transferase Inactivating Macrolides, Encoded by gimA from Streptomyces ambofaciens

In Streptomyces ambofaciens, the producer of the macrolide antibiotic spiramycin, an open reading frame (ORF) was found downstream of srmA, a gene conferring resistance to spiramycin. The deduced product of this ORF had high degrees of similarity to Streptomyces lividans glycosyl transferase, which...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Gourmelen, Anne, Blondelet-Rouault, Marie-Hélène, Pernodet, Jean-Luc
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105906/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756764/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2612
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