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Glycosylation of macrolide antibiotics in extracts of Streptomyces lividans.
Inducible resistance to macrolide antibiotics in Streptomyces lividans involves MGT, a macrolide glycosyl transferase that utilizes UDP-glucose as cofactor. Substrates for MGT include macrolides with 12-, 14-, 15-, or 16-atom cyclic polyketide lactones (as in methymycin, erythromycin, azithromycin,...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1992
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC188440/ https://ncbi.nlm.nih.gov/pubmed/1605601 |
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