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Characterization of a Glycosyl Transferase Inactivating Macrolides, Encoded by gimA from Streptomyces ambofaciens

In Streptomyces ambofaciens, the producer of the macrolide antibiotic spiramycin, an open reading frame (ORF) was found downstream of srmA, a gene conferring resistance to spiramycin. The deduced product of this ORF had high degrees of similarity to Streptomyces lividans glycosyl transferase, which...

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Autores principales: Gourmelen, Anne, Blondelet-Rouault, Marie-Hélène, Pernodet, Jean-Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC105906/
https://ncbi.nlm.nih.gov/pubmed/9756764
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