Antifungal Activity of the Pradimicin Derivative BMS 181184 in the Treatment of Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits

The activity of the pradimicin derivative BMS 181184 was evaluated in a model of invasive pulmonary aspergillosis in persistently neutropenic rabbits and compared with that of amphotericin B deoxycholate. BMS 181184 at total daily doses of 50 and 150 mg/kg of body weight was at least as effective as...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Gonzalez, Corina E., Groll, Andreas H., Giri, Neelam, Shetty, Daiva, Al-Mohsen, Ibrahim, Sein, Tin, Feuerstein, Erwin, Bacher, John, Piscitelli, Stephen, Walsh, Thomas J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2399
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