Antifungal Activity of the Pradimicin Derivative BMS 181184 in the Treatment of Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits

The activity of the pradimicin derivative BMS 181184 was evaluated in a model of invasive pulmonary aspergillosis in persistently neutropenic rabbits and compared with that of amphotericin B deoxycholate. BMS 181184 at total daily doses of 50 and 150 mg/kg of body weight was at least as effective as...

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Bibliografiska uppgifter
Huvudupphovsmän: Gonzalez, Corina E., Groll, Andreas H., Giri, Neelam, Shetty, Daiva, Al-Mohsen, Ibrahim, Sein, Tin, Feuerstein, Erwin, Bacher, John, Piscitelli, Stephen, Walsh, Thomas J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC105840/
https://ncbi.nlm.nih.gov/pubmed/9736570
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