Absence of Effect of Rufloxacin on Theophylline Pharmacokinetics in Steady State

Several quinolone antibacterial agents are known to inhibit the metabolism of theophylline, with the potential to cause adverse events due to raised theophylline concentrations during coadministration. A randomized crossover study was therefore conducted with 12 healthy male volunteers (ages, 23 to...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kinzig-Schippers, Martina, Fuhr, Uwe, Cesana, Marina, Müller, Carola, Staib, A. Horst, Rietbrock, S., Sörgel, Fritz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2359
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