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Absence of Effect of Rufloxacin on Theophylline Pharmacokinetics in Steady State

Several quinolone antibacterial agents are known to inhibit the metabolism of theophylline, with the potential to cause adverse events due to raised theophylline concentrations during coadministration. A randomized crossover study was therefore conducted with 12 healthy male volunteers (ages, 23 to...

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Bibliografiske detaljer
Main Authors: Kinzig-Schippers, Martina, Fuhr, Uwe, Cesana, Marina, Müller, Carola, Staib, A. Horst, Rietbrock, S., Sörgel, Fritz
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105833/
https://ncbi.nlm.nih.gov/pubmed/9736563
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