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Absence of Effect of Rufloxacin on Theophylline Pharmacokinetics in Steady State

Several quinolone antibacterial agents are known to inhibit the metabolism of theophylline, with the potential to cause adverse events due to raised theophylline concentrations during coadministration. A randomized crossover study was therefore conducted with 12 healthy male volunteers (ages, 23 to...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kinzig-Schippers, Martina, Fuhr, Uwe, Cesana, Marina, Müller, Carola, Staib, A. Horst, Rietbrock, S., Sörgel, Fritz
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105833/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736563/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2359
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