Alterations in Topoisomerase IV and DNA Gyrase in Quinolone-Resistant Mutants of Mycoplasma hominis Obtained In Vitro

Mycoplasma hominis mutants were selected stepwise for resistance to ofloxacin and sparfloxacin, and their gyrA, gyrB, parC, and parE quinolone resistance-determining regions were characterized. For ofloxacin, four rounds of selection yielded six first-, six second-, five third-, and two fourth-step...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Bébéar, Cécile M., Renaudin, Hélène, Charron, Alain, Bové, Joseph M., Bébéar, Christiane, Renaudin, Joel
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Mechanisms of Resistance
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105824/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2304
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