Antibacterial Activities and Inhibitory Effects of Sitafloxacin (DU-6859a) and Its Optical Isomers against Type II Topoisomerases

The in vitro inhibitory effects of sitafloxacin (DU-6859a) and its three stereoisomers on bacterial DNA gyrase from Escherichia coli, topoisomerase IV from Staphylococcus aureus, and topoisomerase II from human placenta were compared. No correlation was observed between the inhibitory activities of...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Akasaka, Takaaki, Kurosaka, Seiko, Uchida, Yoko, Tanaka, Mayumi, Sato, Kenichi, Hayakawa, Isao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1284
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