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Antibacterial Activities and Inhibitory Effects of Sitafloxacin (DU-6859a) and Its Optical Isomers against Type II Topoisomerases

The in vitro inhibitory effects of sitafloxacin (DU-6859a) and its three stereoisomers on bacterial DNA gyrase from Escherichia coli, topoisomerase IV from Staphylococcus aureus, and topoisomerase II from human placenta were compared. No correlation was observed between the inhibitory activities of...

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Main Authors: Akasaka, Takaaki, Kurosaka, Seiko, Uchida, Yoko, Tanaka, Mayumi, Sato, Kenichi, Hayakawa, Isao
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC105807/
https://ncbi.nlm.nih.gov/pubmed/9593169
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