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Antibacterial Activities and Inhibitory Effects of Sitafloxacin (DU-6859a) and Its Optical Isomers against Type II Topoisomerases

The in vitro inhibitory effects of sitafloxacin (DU-6859a) and its three stereoisomers on bacterial DNA gyrase from Escherichia coli, topoisomerase IV from Staphylococcus aureus, and topoisomerase II from human placenta were compared. No correlation was observed between the inhibitory activities of...

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Bibliographische Detailangaben
Hauptverfasser: Akasaka, Takaaki, Kurosaka, Seiko, Uchida, Yoko, Tanaka, Mayumi, Sato, Kenichi, Hayakawa, Isao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105807/
https://ncbi.nlm.nih.gov/pubmed/9593169
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