Antibacterial Activities and Inhibitory Effects of Sitafloxacin (DU-6859a) and Its Optical Isomers against Type II Topoisomerases

The in vitro inhibitory effects of sitafloxacin (DU-6859a) and its three stereoisomers on bacterial DNA gyrase from Escherichia coli, topoisomerase IV from Staphylococcus aureus, and topoisomerase II from human placenta were compared. No correlation was observed between the inhibitory activities of...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Akasaka, Takaaki, Kurosaka, Seiko, Uchida, Yoko, Tanaka, Mayumi, Sato, Kenichi, Hayakawa, Isao
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1998
Fag:	Mechanisms of Action: Physiological Effects
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1284
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