Identification of Saccharomyces cerevisiae Genes Conferring Resistance to Quinoline Ring-Containing Antimalarial Drugs

To identify genes that can confer resistance to antimalarial drugs in yeast, we transformed the quinidine-sensitive strain CYX247-9A of Saccharomyces cerevisiae with a yeast genomic library and selected for transformants that grow in the presence of elevated levels of antimalarial drugs. Plasmids we...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Delling, Ulrike, Raymond, Martine, Schurr, Erwin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1034
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