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Identification of Saccharomyces cerevisiae Genes Conferring Resistance to Quinoline Ring-Containing Antimalarial Drugs

To identify genes that can confer resistance to antimalarial drugs in yeast, we transformed the quinidine-sensitive strain CYX247-9A of Saccharomyces cerevisiae with a yeast genomic library and selected for transformants that grow in the presence of elevated levels of antimalarial drugs. Plasmids we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Delling, Ulrike, Raymond, Martine, Schurr, Erwin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105740/
https://ncbi.nlm.nih.gov/pubmed/9593122
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