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Efficacy of MK-991 (L-743,872), a Semisynthetic Pneumocandin, in Murine Models of Pneumocystis carinii

In addition to its potent efficacy in animal models against Candida sp., Aspergillus fumigatus, and Histoplasma capsulatum, the clinical candidate pneumocandin MK-991 (formerly L-743,872) was also extremely potent against Pneumocystis carinii in models of immune-compromised animals. MK-991 was appro...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Powles, Mary Ann, Liberator, Paul, Anderson, Jennifer, Karkhanis, Yashwant, Dropinski, James F., Bouffard, F. Aileen, Balkovec, James M., Fujioka, Hisashi, Aikawa, Masamichi, McFadden, Diane, Schmatz, Dennis
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9687394/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.8.1985
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