Efficacy of MK-991 (L-743,872), a Semisynthetic Pneumocandin, in Murine Models of Pneumocystis carinii

In addition to its potent efficacy in animal models against Candida sp., Aspergillus fumigatus, and Histoplasma capsulatum, the clinical candidate pneumocandin MK-991 (formerly L-743,872) was also extremely potent against Pneumocystis carinii in models of immune-compromised animals. MK-991 was appro...

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Detalhes bibliográficos
Main Authors: Powles, Mary Ann, Liberator, Paul, Anderson, Jennifer, Karkhanis, Yashwant, Dropinski, James F., Bouffard, F. Aileen, Balkovec, James M., Fujioka, Hisashi, Aikawa, Masamichi, McFadden, Diane, Schmatz, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105720/
https://ncbi.nlm.nih.gov/pubmed/9687394
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