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Dosing of Aminoglycosides To Rapidly Attain Pharmacodynamic Goals and Hasten Therapeutic Response by Using Individualized Pharmacokinetic Monitoring of Patients with Pneumonia Caused by Gram-Negative Organisms

Achieving a peak aminoglycoside concentration (C(max))/MIC of ≥10 within 48 h of initiation of therapy for pneumonia caused by gram-negative organisms results in a 90% probability of therapeutic response by day 7. Targeting an MIC of 1 μg/ml, empirical aminoglycoside loading doses of 348 (25th- to 7...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Antimicrob Agents Chemother
Ngā kaituhi matua: Kashuba, A. D. M., Bertino, J. S., Nafziger, A. N.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology (ASM) 1998
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9661031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.7.1842
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