Ribosomes from an Oxazolidinone-Resistant Mutant Confer Resistance to Eperezolid in a Staphylococcus aureus Cell-Free Transcription-Translation Assay

Oxazolidinone-resistant mutants of Staphylococcus aureus, isolated with a spiral plating technique, had a 16-fold higher MIC (2 versus 32 μg/ml) of eperezolid when compared to the parental sensitive strain. Eperezolid inhibited in vitro protein translation with 50% inhibitory concentrations of 30 μM...

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Detaylı Bibliyografya

Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Murray, Robert W., Schaadt, Ronda D., Zurenko, Gary E., Marotti, Keith R.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1998
Konular:	Mechanisms of Resistance
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.947
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