Zidovudine Pharmacokinetics in Premature Infants Exposed to Human Immunodeficiency Virus

We used population analysis techniques to determine zidovudine (ZDV) pharmacokinetic parameters in 15 preterm neonates (mean gestational age, 29.4 weeks; mean birth weight, 1,230 g) at a mean age of 5.5 days. The values of the pharmacokinetic parameters were as follows: clearance, 2.53 ± 0.44 ml/min...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Mirochnick, Mark, Capparelli, Edmund, Dankner, Wayne, Sperling, Rhoda S., van Dyke, Russ, Spector, Stephen A.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105546/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.808
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