Zidovudine Pharmacokinetics in Premature Infants Exposed to Human Immunodeficiency Virus

We used population analysis techniques to determine zidovudine (ZDV) pharmacokinetic parameters in 15 preterm neonates (mean gestational age, 29.4 weeks; mean birth weight, 1,230 g) at a mean age of 5.5 days. The values of the pharmacokinetic parameters were as follows: clearance, 2.53 ± 0.44 ml/min...

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Detalhes bibliográficos
Main Authors: Mirochnick, Mark, Capparelli, Edmund, Dankner, Wayne, Sperling, Rhoda S., van Dyke, Russ, Spector, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105546/
https://ncbi.nlm.nih.gov/pubmed/9559787
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