Pharmacokinetics of Intravenous Acyclovir, Zidovudine, and Acyclovir-Zidovudine in Pregnant Rats

The pharmacokinetics and placental transfer of acyclovir and zidovudine monotherapies and acyclovir-zidovudine combination therapy were compared in the pregnant rat. Timed-pregnancy Sprague-Dawley rats were used for the study. Doses of 60 mg of each drug/kg of body weight in monotherapy and in combi...

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Hlavní autoři: Brown, Stacy D., Bartlett, Michael G., White, Catherine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149315/
https://ncbi.nlm.nih.gov/pubmed/12604532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.991-996.2003
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