Duration and Clinical Relevance of Postantibiotic Effect in Relation to the Dosing Interval
The influence of half-life on the postantibiotic effect (PAE) of tobramycin against Pseudomonas aeruginosa and Staphylococcus aureus was investigated during one dosing interval. Tobramycin half-lives of 0.5 to 2.5 h were simulated in an in vitro model, and the PAE was determined by an enzymatic inac...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9559777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.4.749 |
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