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Single-dose accumulation pharmacokinetics of tobramycin and netilmicin in normal volunteers.

The two-compartment tissue accumulation pharmacokinetics of tobramycin and netilmicin were compared in 11 normal volunteers by using a crossover design. After each 1.0-mg/kg (body weight) dose, serum was collected for 96 h, and complete 24-h urine collections were obtained for a total of 30 days. Tw...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Winslade, N E, Adelman, M H, Evans, E J, Schentag, J J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3606064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.4.605
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