Neurotoxicodynamics of the Interaction between Ciprofloxacin and Foscarnet in Mice

The potential for convulsions induced by the coadministration of ciprofloxacin (CPFX) and foscarnet (PFA) may be due not to a change in the distribution of CPFX to the brain but to a potential CPFX-induced inhibition of γ-aminobutyric acid (GABA)-GABA(A) receptor binding in the presence of PFA.

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Matsuo, Hirotami, Ryu, Miwako, Nagata, Aya, Uchida, Takahiro, Kawakami, Jun-Ichi, Yamamoto, Koujirou, Iga, Tatsuji, Sawada, Yasufumi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9517953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.3.691
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