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Inhibition of Acute-, Latent-, and Chronic-Phase Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Bistriazoloacridone Analog That Selectively Inhibits HIV-1 Transcription

Nanomolar concentrations of temacrazine (1,4-bis[3-(6-oxo-6H-v-triazolo[4,5,1-de]acridin-5-yl)amino-propyl]piperazine) were discovered to inhibit acute human immunodeficiency virus type 1 (HIV-1) infections and suppress the production of virus from chronically and latently infected cells containing...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Turpin, Jim A., Buckheit, Robert W., Derse, David, Hollingshead, Melinda, Williamson, Karen, Palamone, Carla, Osterling, M. Clayton, Hill, Shawn A., Graham, Lisa, Schaeffer, Catherine A., Bu, Ming, Huang, Mingjun, Cholody, Wieslaw M., Michejda, Christopher J., Rice, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105487/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9517921/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.3.487
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