Inhibition of Acute-, Latent-, and Chronic-Phase Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Bistriazoloacridone Analog That Selectively Inhibits HIV-1 Transcription

Nanomolar concentrations of temacrazine (1,4-bis[3-(6-oxo-6H-v-triazolo[4,5,1-de]acridin-5-yl)amino-propyl]piperazine) were discovered to inhibit acute human immunodeficiency virus type 1 (HIV-1) infections and suppress the production of virus from chronically and latently infected cells containing...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Turpin, Jim A., Buckheit, Robert W., Derse, David, Hollingshead, Melinda, Williamson, Karen, Palamone, Carla, Osterling, M. Clayton, Hill, Shawn A., Graham, Lisa, Schaeffer, Catherine A., Bu, Ming, Huang, Mingjun, Cholody, Wieslaw M., Michejda, Christopher J., Rice, William G.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9517921/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.3.487
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