The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II
The lantibiotic mersacidin exerts its bactericidal action by inhibition of peptidoglycan biosynthesis. It interferes with the membrane-associated transglycosylation reaction; during this step the ultimate monomeric peptidoglycan precursor, undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)-GlcNAc (li...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9449277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.1.154 |
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