Treatment of Histoplasmosis with MK-991 (L-743,872)

BALB/c nu/+ immunocompetent and athymic (nu/nu) mice were infected intravenously with yeast cells of Histoplasma capsulatum. Mice were either given water (controls) intraperitoneally (i.p.) or given MK-991 i.p. once daily or twice daily. Protection was measured as prolonged survival or reduction in...

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Hlavní autoři: Graybill, John R., Najvar, Laura K., Montalbo, Eleanor M., Barchiesi, Francesco J., Luther, Michael F., Rinaldi, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC105471/
https://ncbi.nlm.nih.gov/pubmed/9449276
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