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Treatment of Histoplasmosis with MK-991 (L-743,872)

BALB/c nu/+ immunocompetent and athymic (nu/nu) mice were infected intravenously with yeast cells of Histoplasma capsulatum. Mice were either given water (controls) intraperitoneally (i.p.) or given MK-991 i.p. once daily or twice daily. Protection was measured as prolonged survival or reduction in...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Graybill, John R., Najvar, Laura K., Montalbo, Eleanor M., Barchiesi, Francesco J., Luther, Michael F., Rinaldi, Michael G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105471/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9449276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.1.151
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